- Individually a Rat has a weak bite causing a pretty trivial rupture effect and is easily killed using a pistol.
- The Rat is a swarm creature and will attack in number posing a more formidable threat to the player.
- Rats are able to climb stairs with ease but are unable to climb ladders.
- The player should seek higher ground if faced with large numbers of these mutants and pick them off with cheap pistol ammunition. A desk is sufficient.
- Against large concentrations, Grenades are not really that effective and may inflict unnecessary damage on the player anyway. Shotguns are certainly effective but many might consider their use to be a waste of resources.